Nctm1^MSM
QTL Variant Detail

Summary

• QTL variant: Nctm1^MSM
• Name: Nakano cataract modifier 1; MSM
• MGI ID: MGI:3033718
• QTL: Nctm1 Location: Chr3:97698638-100373060 bp Genetic Position: Chr3, cM position of peak correlated region/allele: 42.04 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: MSM

Variant description

• Allele Type: QTL
• Inheritance: Dominant

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:80817

The authors indicated that in the BALB/c-nct/nct x BALB/c-nct/nct x MSM backcross there were two loci that modified the expression of Chromosome 16 marker nct. One modifier (Nctm1) mapped between D3Mit41 and D3Mit12, while the other (Nctm2) mapped with D10Mit151, with chi-squares of 13.1 and 8.3 respectively.

References

• Original: J:80817 Narita M, et al., Genetic analysis of Nakano Cataract and its modifier genes in mice. Exp Eye Res. 2002 Dec;75(6):745-51
• All: 1 reference(s)