Taf8^{Gt(pGT1.8geo)9Pgr}
Gene trapped Allele Detail

Summary

• Symbol: Taf8^{Gt(pGT1.8geo)9Pgr}
• Name: TATA-box binding protein associated factor 8; gene trap 9, Peter Gruss
• MGI ID: MGI:3033758
• Synonyms: Tbn^gt
• Gene: Taf8 Location: Chr17:47794289-47813216 bp, - strand Genetic Position: Chr17, 23.33 cM, cytoband C
• Alliance: Taf8^{Gt(pGT1.8geo)9Pgr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:65596
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted into the endogenous gene such that the lacZ and neomycin genes were fused to the expressed mRNA at position 66. Beta-galactosidase expression was noted in a similar pattern to the wild-type mRNA. (J:65596)

Expression

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taf8 Mutation: 27 strains or lines available

References

• Original: J:65596 Voss AK, et al., Taube nuss is a novel gene essential for the survival of pluripotent cells of early mouse embryos. Development. 2000 Dec;127(24):5449-61
• All: 1 reference(s)