Summary |
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Variant origin |
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Variant description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Expression |
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:79991Notch-mild C57BL/6J mice 129 F2-Psen -/- mice were informative in mapping a modifier of Notch to mouse Chromosome 1 with a LOD score of ~ 6.0 with D1Mit150. Nicastrin (9430068N19Rik) and Presenilin 2 also mapped to this region. The authors concludedthat PS2 ( Presenilin 2) is unlikely to be the modifier, whereas more analysis is required for Nicastrin. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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