Nnc1^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Nnc1^DBA/2J
• Name: neuron number control 1; DBA/2J
• MGI ID: MGI:3036085
• QTL: Nnc1 Location: unknown Genetic Position: Chr11, Syntenic

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased retinal ganglion cell numbers compared to C57BL/6J. (J:45194)
• Inheritance: Other (see notes)

Notes

Nnc1 exhibits additive inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:45194

Using BXH and BXD RI lines, a quantitative locus, Nnc1 , was mapped to mouse Chromosome 11 between Hoxb and Krt1 in the region of the Tstap91a locus. Nnc1 is involved with determining retinal ganglion numbers in mice.

References

• Original: J:45194 Williams RW, et al., Natural variation in neuron number in mice is linked to a major quantitative trait locus on Chr 11. J Neurosci. 1998 Jan 1;18(1):138-46
• All: 1 reference(s)