Omlr^DDK
QTL Variant Detail

Summary

• QTL variant: Omlr^DDK
• Name: om-linked responder; DDK
• MGI ID: MGI:3036091
• QTL: Omlr Location: unknown Genetic Position: Chr11, Syntenic

Variant origin

• Strain of Specimen: DDK

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:62125

Matings between (C57BL/6 x DDK)F1 females and C57BL/6 males result in preferential inheritance of the DDK allele which is referred to as transmission ratio distortion (TRD). TRD shows linkage to the Om locus on mouse Chromosome 11 and is likely dependentupon maternal heterozygosity as well as the genotype of the fertilizing sperm at this locus. Linkage to TRD was detected near D11Mit66. Fine mapping resolved this locus, the Om-linked responder (Omlr) locus, to a 0.32 cM interval on mouse Chromosome 11 between D11Spn1 and Ccl5 at approximately 48 cM.

References

• Original: J:62125 Pardo-Manuel De Villena F, et al., Heritability of the maternal meiotic drive system linked to Om and high-resolution mapping of the Responder locus in mouse. Genetics. 2000 May;155(1):283-9
• All: 1 reference(s)