Summary |
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Variant origin |
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Variant description |
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:62125Matings between (C57BL/6 x DDK)F1 females and C57BL/6 males result in preferential inheritance of the DDK allele which is referred to as transmission ratio distortion (TRD). TRD shows linkage to the Om locus on mouse Chromosome 11 and is likely dependentupon maternal heterozygosity as well as the genotype of the fertilizing sperm at this locus. Linkage to TRD was detected near D11Mit66. Fine mapping resolved this locus, the Om-linked responder (Omlr) locus, to a 0.32 cM interval on mouse Chromosome 11 between D11Spn1 and Ccl5 at approximately 48 cM. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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