Slc25a5^tm1Dwa
Targeted Allele Detail

Summary

• Symbol: Slc25a5^tm1Dwa
• Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5; targeted mutation 1, Douglas C Wallace
• MGI ID: MGI:3036322
• Synonyms: Ant2^fl
• Gene: Slc25a5 Location: ChrX:36059304-36062460 bp, + strand Genetic Position: ChrX, 21.2 cM, cytoband A4
• Alliance: Slc25a5^tm1Dwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:88165
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 and 4 as well as a PGK-neomycin cassette inserted in a 3' position were flanked by two loxP sites. (J:88165)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc25a5 Mutation: 8 strains or lines available

References

• Original: J:88165 Kokoszka JE, et al., The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature. 2004 Jan 29;427(6973):461-5
• All: 4 reference(s)