Napa^tm1Caw
Targeted Allele Detail

Summary

• Symbol: Napa^tm1Caw
• Name: N-ethylmaleimide sensitive fusion protein attachment protein alpha; targeted mutation 1, Christopher A Walsh
• MGI ID: MGI:3036672
• Gene: Napa Location: Chr7:15832383-15851900 bp, + strand Genetic Position: Chr7, 8.74 cM
• Alliance: Napa^tm1Caw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:88495
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector pKO-Napa replaces coding exons 2 and 3 with BetaGal and a neomycin cassette. This results in a translational frameshift and premature termination in exon 4. (J:88495)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Napa Mutation: 16 strains or lines available

References

• Original: J:88495 Chae TH, et al., The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004 Mar;36(3):264-70
• All: 1 reference(s)