Idd9.1^C57BL/10SnJ
QTL Variant Detail

Summary

• QTL variant: Idd9.1^C57BL/10SnJ
• Name: insulin dependent diabetes susceptibility 9.1; C57BL/10SnJ
• MGI ID: MGI:3036805
• QTL: Idd9.1 Location: unknown Genetic Position: Chr4, Syntenic

Variant origin

• Strain of Specimen: C57BL/10SnJ

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers resistance to insulin dependent diabetes compared to NOD/MrkTac. (J:63670)

Notes

This allele also confers increased iNKT cell numbers and restores IFN-gamma response in NK cells on an NOD genetic background (J:85823).

References

• Original: J:63670 Lyons PA, et al., The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137. Immunity. 2000 Jul;13(1):107-15
• All: 5 reference(s)