Idd18^C57BL/6
QTL Variant Detail

Summary

• QTL variant: Idd18^C57BL/6
• Name: insulin dependent diabetes susceptibility 18; C57BL/6
• MGI ID: MGI:3036823
• QTL: Idd18 Location: unknown Genetic Position: Chr3, Syntenic

Variant origin

• Strain of Specimen: C57BL/6

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers resistance to insulin dependent diabetes compared to NOD.
• Inheritance: Not Specified

Notes

Idd10 and Idd18 interact to promote disease resistance. Homozygosity for C57BL/6-derived alleles at both Idd10 and Idd18 confers significantly increased resistance to type 1 diabetes.

References

• Original: J:46659 Podolin PL, et al., Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3. Mamm Genome. 1998 Apr;9(4):283-6
• All: 5 reference(s)