Celf4^Ff
Transgenic Allele Detail

Summary

• Symbol: Celf4^Ff
• Name: CUGBP, Elav-like family member 4; frequent flyer
• MGI ID: MGI:3037035
• Synonyms: Ff
• Gene: Celf4 Location: Chr18:25610689-25887214 bp, - strand Genetic Position: Chr18, 13.92 cM, cytoband B1
• Alliance: Celf4^Ff page

Celf4^Ff/Brunol4⁺ mice exhibit seizures

Show the 1 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic
• Mutation: Insertion
• Mutation details: Multiple copies (>3) of a non-expressing transgene inserted into the first intron of the gene. In total RNA samples from newborn mice, no transcript of the endogenous gene was detected in homozygotes and approximately 45% reduction was seen in heterozygotes. (J:123744)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Celf4 Mutation: 27 strains or lines available

References

• Original: J:123744 Yang Y, et al., Complex seizure disorder caused by Brunol4 deficiency in mice. PLoS Genet. 2007 Jul 27;3(7):e124
• All: 2 reference(s)