Nr4a3^tm1Omc
Targeted Allele Detail

Summary

• Symbol: Nr4a3^tm1Omc
• Name: nuclear receptor subfamily 4, group A, member 3; targeted mutation 1, Orla M Conneely
• MGI ID: MGI:3037444
• Synonyms: nor-1^-
• Gene: Nr4a3 Location: Chr4:48045153-48086447 bp, + strand Genetic Position: Chr4, 26.07 cM, cytoband B2
• Alliance: Nr4a3^tm1Omc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73971
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ gene and neomycin selection cassette were inserted into exon 2. Beta-galactosidase was expressed from this allele in a pattern similar to the endogenous gene. (J:73971)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nr4a3 Mutation: 54 strains or lines available

References

• Original: J:73971 Ponnio T, et al., The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear. Mol Cell Biol. 2002 Feb;22(3):935-45
• All: 21 reference(s)