Tg(CD19-cre/ERT2)1Cgn
Transgene Detail

Summary

• Symbol: Tg(CD19-cre/ERT2)1Cgn
• Name: transgene insertion 1, University of Cologne
• MGI ID: MGI:3037896
• Synonyms: CD19-Cre, hCD19-CreERT2
• Transgene: Tg(CD19-cre/ERT2)1Cgn Location: unknown
• Alliance: Tg(CD19-cre/ERT2)1Cgn page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(CD19-cre/ERT2)1Cgn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CD19 (930)

  Cd19	(MGI:88319)

• Mutation details: This transgene expresses a tamoxifen-inducible form of cre recombinase from the human B cell-specific CD19 promoter. (J:88472)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CD19 (human) Summary of all recombinase alleles driven by CD19. Alliance human CD19 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:88472 Casola S, et al., B cell receptor signal strength determines B cell fate. Nat Immunol. 2004 Mar;5(3):317-27
• All: 13 reference(s)