Cd93^tm1Mbo
Targeted Allele Detail

Summary

• Symbol: Cd93^tm1Mbo
• Name: CD93 antigen; targeted mutation 1, Marina Botto
• MGI ID: MGI:3038703
• Synonyms: CD93^-
• Gene: Cd93 Location: Chr2:148278571-148285455 bp, - strand Genetic Position: Chr2, 73.48 cM
• Alliance: Cd93^tm1Mbo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:88610
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin cassette replaced an 1128 bp fragment in exon 1. Absence of mRNA and protein expression was confirmed by RT-PCR and FACS analysis on peritoneal macrophages and immature B cells respectively. (J:88610)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd93 Mutation: 21 strains or lines available

References

• Original: J:88610 Norsworthy PJ, et al., Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol. 2004 Mar 15;172(6):3406-14
• All: 13 reference(s)