Calcrtm1Dgal
Targeted Allele Detail
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Symbol: |
Calcrtm1Dgal |
Name: |
calcitonin receptor; targeted mutation 1, D L Galson |
MGI ID: |
MGI:3038975 |
Synonyms: |
Calcr-, CTR - |
Gene: |
Calcr Location: Chr6:3685680-3764714 bp, - strand Genetic Position: Chr6, 1.81 cM
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Alliance: |
Calcrtm1Dgal page
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Germline Transmission: |
Earliest citation of germline transmission:
J:92983
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Homologous recombination was used to replace exons 6 and 7 with a neomycin cassette in the reverse orientation to the endogenous allele. Real time PCR demonstrated that expression of heterozygous osteoclasts was decreased compared with that of wild-type.
(J:92983)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Calcr Mutation: |
59 strains or lines available
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Original: |
J:92983 Laplace C, et al., (Homozygous deletion of the murine calcitonin receptor gene is an embryonic lethal). Abstracts of the 24th Annual Meeting of the American Society for Bone and Mineral Research. San Antonio, Texas, USA. September 20-24, 2002. J Bone Miner Res. 2002;17 Suppl 1:S125-541 (S143) |
All: |
2 reference(s) |
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