Llgl1^tm1Vv
Targeted Allele Detail

Summary

• Symbol: Llgl1^tm1Vv
• Name: LLGL1 scribble cell polarity complex component; targeted mutation 1, Valeri Vasioukhin
• MGI ID: MGI:3039268
• Gene: Llgl1 Location: Chr11:60590549-60605012 bp, + strand Genetic Position: Chr11, 37.81 cM
• Alliance: Llgl1^tm1Vv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89028
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The exon immediately downstream of the first coding exon was left flanked by single loxP sites following cre-mediated excision of an IRES-betageo cassette used for selection. (J:89028)

Expression

In Mice Carrying this Mutation:	38 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Llgl1 Mutation: 63 strains or lines available

References

• Original: J:89028 Klezovitch O, et al., Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev. 2004 Mar 1;18(5):559-71
• All: 16 reference(s)