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Tg(Apoe-Lepr)1Kry
Transgene Detail
Summary
Symbol: Tg(Apoe-Lepr)1Kry
Name: transgene insertion 1, Gerard Karsenty
MGI ID: MGI:3039273
Synonyms: ApoE-ObRe
Transgene: Tg(Apoe-Lepr)1Kry  Location: unknown  
Alliance: Tg(Apoe-Lepr)1Kry page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Apoe-Lepr)1Kry expresses 1 gene
 
Mutation detailsAn isoform of Lepr cDNA lacking the transmembrane domain found in all other isoforms was cloned 3' of the liver specific Apoe promoter and 5' of liver specific enhancer sequence. (J:88655)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:88655 Elefteriou F, et al., Serum leptin level is a regulator of bone mass. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):3258-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory