Efnb1^tm1Sor
Targeted Allele Detail

Summary

• Symbol: Efnb1^tm1Sor
• Name: ephrin B1; targeted mutation 1, Philippe Soriano
• MGI ID: MGI:3039289
• Synonyms: ephrin-B1^lox
• Gene: Efnb1 Location: ChrX:98179736-98192597 bp, + strand Genetic Position: ChrX, 43.22 cM, cytoband D
• Alliance: Efnb1^tm1Sor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89008
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 2 through 5 were flanked by single loxP sites inserted by homologous recombination. A PGK-neo-bpA cassette flanked by FRT sites remained downstream of the coding region. (J:89008)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Efnb1 Mutation: 15 strains or lines available

References

• Original: J:89008 Davy A, et al., Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 2004 Mar 1;18(5):572-83
• All: 31 reference(s)