Tg(TacLIZa)A1Jsh
Transgene Detail

Summary

• Symbol: Tg(TacLIZa)A1Jsh
• Name: transgene insertion A1, Jay M Short
• MGI ID: MGI:3039672
• Synonyms: Big Blue, BigBlue
• Transgene: Tg(TacLIZa)A1Jsh Location: unknown
• Alliance: Tg(TacLIZa)A1Jsh page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains a lambda phage vector (LIZ) containing the wild-type allele of the bacterial lacI gene. Slot blot and Southern analyses estimated the A1 line carries about 30 copies of the transgene, which integrated as a head to tail concatemer at a single locus with no detectable rearrangements. (J:82962)

Tumor Data

List all tumor models in MMHCdb carrying Tg(TacLIZa)A1Jsh

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

The transgenics are known as Big Blue mice.

References

• Original: J:82962 Kohler SW, et al., Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):7958-62
• All: 36 reference(s)