Tg(IghMyc)186Brn
Transgene Detail

Summary

• Symbol: Tg(IghMyc)186Brn
• Name: transgene insertion 186, Anton Berns
• MGI ID: MGI:3039690
• Synonyms: Emu-myc
• Transgene: Tg(IghMyc)186Brn Location: unknown
• Alliance: Tg(IghMyc)186Brn page

Transgene origin

• Strain of Origin: (CBA/BrA x C57BL/LiA)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IghMyc)186Brn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myc (MGI:97250)

• Mutation details: The mouse myelocytomatosis oncogene cDNA expressed under control of the mouse Igh (Emu) enhancer and mouse Myc promoter. Expression is restricted to the B cell lineage. (J:71550)

Tumor Data

List all tumor models in MMHCdb carrying Tg(IghMyc)186Brn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Line 186 is a representative transgene. Three transgenic lines were produced; line used not specified.

References

• Original: J:71550 Verbeek S, et al., Mice bearing the E mu-myc and E mu-pim-1 transgenes develop pre-B-cell leukemia prenatally. Mol Cell Biol. 1991 Feb;11(2):1176-9
• All: 11 reference(s)