Ptprv^tm1Asmi
Targeted Allele Detail

Summary

• Symbol: Ptprv^tm1Asmi
• Name: protein tyrosine phosphatase receptor type V; targeted mutation 1, A Smith
• MGI ID: MGI:3039948
• Synonyms: Esp^-, Esp-nLacZ, Ptprv-LacZ
• Gene: Ptprv Location: Chr1:135036236-135060313 bp, - strand Genetic Position: Chr1, 58.24 cM, cytoband F-G
• Alliance: Ptprv^tm1Asmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89221
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 6 thru 35 were replaced with an IRES-LacZ-pgk-HPRT cassette via homologous recombination. X-Gal staining confirmed expression of the mutant allele in adult ovary and Sertoli cells. (J:89221)

Expression

In Mice Carrying this Mutation:	35 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprv Mutation: 30 strains or lines available

References

• Original: J:89221 Dacquin R, et al., Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34
• All: 8 reference(s)