Tg(RIR-Tag)87Dh
Transgene Detail

Summary

• Symbol: Tg(RIR-Tag)87Dh
• Name: transgene insertion 87, Douglas Hanahan
• MGI ID: MGI:3040264
• Transgene: Tg(RIR-Tag)87Dh Location: unknown
• Alliance: Tg(RIR-Tag)87Dh page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the rat insulin 2 promoter and the wild-type allele of the SV40 large T antigen (Tag) gene. (J:50695)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Line 87, the only line produced, carries a single copy of the transgene. Transgenic mice die prematurely at 9-12 weeks of age.

References

• Original: J:50695 Hanahan D, Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature. 1985 May 9-15;315(6015):115-22
• All: 1 reference(s)