Tg(rTH-Tag)20Dmc
Transgene Detail

Summary

• Symbol: Tg(rTH-Tag)20Dmc
• Name: transgene insertion 20, Dona M Chikaraishi
• MGI ID: MGI:3040267
• Synonyms: TgN(rTH-Tag)20Dmc)
• Transgene: Tg(rTH-Tag)20Dmc Location: unknown
• Alliance: Tg(rTH-Tag)20Dmc page

Transgene origin

• Strain of Origin: (C57BL/6NTac x DBA/2NTac)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the rat tyrosine hydroxylase promoter and the wild-type allele of the SV40 large T antigen (Tag) gene. The construct also includes the rat tyrosine hydroxylase enhancer. (J:90323)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(rTH-Tag)20Dmc

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Transgenic mice on a genetic background involving C57BL/6Tac and DBA/2Tac display bone and brain stem tumors.

References

• Original: J:90323 Suri C, et al., Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. J Neurosci. 1993 Mar;13(3):1280-91
• All: 3 reference(s)