Tg(MMTVTGFA)29Rjc
Transgene Detail

Summary

• Symbol: Tg(MMTVTGFA)29Rjc
• Name: transgene insertion 29, Robert J Coffey
• MGI ID: MGI:3040871
• Transgene: Tg(MMTVTGFA)29Rjc Location: unknown
• Alliance: Tg(MMTVTGFA)29Rjc page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTVTGFA)29Rjc expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TGFA (7039)

  Tgfa	(MGI:98724)

• Mutation details: This transgene contains the mouse mammary tumor virus LTR and the normal allele of the human transforming growth factor alpha gene. The vector also contains exons 2 and 3 of the rabbit beta-globin gene. Lines 254, 257, 64 and 29 were produced. (J:28453)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTVTGFA)29Rjc

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:28453 Matsui Y, et al., Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice. Cell. 1990 Jun 15;61(6):1147-55
• All: 15 reference(s)