Pparg^tm1.2Mtz
Targeted Allele Detail

Summary

• Symbol: Pparg^tm1.2Mtz
• Name: peroxisome proliferator activated receptor gamma; targeted mutation 1.2, Daniel Metzger
• MGI ID: MGI:3041451
• Synonyms: PPARgammaL2, Pparg^fl
• Gene: Pparg Location: Chr6:115337912-115467360 bp, + strand Genetic Position: Chr6, 53.41 cM, cytoband E3-F1
• Alliance: Pparg^tm1.2Mtz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89238
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Cre-mediated recombination of Pparg^tm1Mtz excised the floxed neo, leaving exons 1 and 2 floxed. PCR confirmed recombination. (J:89238)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pparg Mutation: 41 strains or lines available

References

• Original: J:89238 Imai T, et al., Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A. 2004 Apr 30;101(13):4543-7
• All: 26 reference(s)