Sox9^tm2.1Crm
Targeted Allele Detail

Summary

• Symbol: Sox9^tm2.1Crm
• Name: SRY (sex determining region Y)-box 9; targeted mutation 2.1, Benoit de Crombrugghe
• MGI ID: MGI:3041881
• Synonyms: Sf1: Cre(5), Sox9^-, Sox9^delta
• Gene: Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
• Alliance: Sox9^tm2.1Crm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89368
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed fragment encompassing exon 2, exon 3, and a neo cassette was excised via cre mediated recombination in the germline. (J:89368)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox9 Mutation: 33 strains or lines available

References

• Original: J:89368 Chaboissier MC, et al., Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development. 2004 May;131(9):1891-901
• All: 6 reference(s)