Tg(Sry)1Ei
Transgene Detail

Summary

• Symbol: Tg(Sry)1Ei
• Name: transgene insertion 1, Eva M Eicher
• MGI ID: MGI:3041981
• Synonyms: Tg(Sry-129)1Ei
• Transgene: Tg(Sry)1Ei Location: unknown
• Alliance: Tg(Sry)1Ei page

Transgene origin

• Strain of Origin: C57BL/6JEi-Chr Y^AKR

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Sry)1Ei expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sry (MGI:98660)

• Mutation details: This transgene consists of an inbred 129 strain derived 14.6 Kb genomic fragment containing the entire Sry open reading frame and no other genes. (J:71077)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Three transgenic lines (referred to as TgN(Sry-129)1Ei, TgN(Sry-129)2Ei, and TgN(Sry-129)3Ei were generated which all produced sex-reversed XX transgenic male offspring. No copy number or insertion location information was provided.

References

• Original: J:71077 Washburn LL, et al., C57BL/6J-T-Associated Sex Reversal in Mice Is Caused by Reduced Expression of a Mus domesticus Sry Allele. Genetics. 2001 Aug;158(4):1675-81
• All: 1 reference(s)