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T41H
Chemically induced Allele Detail
Summary
Symbol: T41H
Name: brachyury, T-box transcription factor T; brachury 41 Harwell
MGI ID: MGI:3042261
Gene: T  Location: Chr17:8653255-8661328 bp, + strand  Genetic Position: Chr17, 4.92 cM
Alliance: T41H page
Mutation
origin
Strain of Origin:  C3H.Cg-Foxq1sa/H
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Nucleotide substitutions
 
Mutation detailsA missense mutation caused a substitution of phenylanlanine for the absolutely conserved isoleucine at position 203 in the fifth T-box domain. (J:93195)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any T Mutation:  59 strains or lines available
Notes
Mice homozygous for the 'satin' locus were mutagenised.
References
Original:  J:93195 Bogani D, et al., New semidominant mutations that affect mouse development. Genesis. 2004 Oct;40(2):109
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory