T^c-3H
Chemically induced Allele Detail

Summary

• Symbol: T^c-3H
• Name: brachyury, T-box transcription factor T; curtailed 3 Harwell
• MGI ID: MGI:3042264
• Gene: T Location: Chr17:8653255-8661328 bp, + strand Genetic Position: Chr17, 4.92 cM
• Alliance: T^c-3H page

Mutation origin

• Strain of Origin: BALB/cOlaHsd

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: The T^c-3H allele is caused by a splice donor mutation at the end of exon 7. A protein truncation, either due to exon skipping or to read-through of the donor site causing an altered open reading frame beyond amino acid 344, is predicted. (J:93195)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any T Mutation: 59 strains or lines available

References

• Original: J:93195 Bogani D, et al., New semidominant mutations that affect mouse development. Genesis. 2004 Oct;40(2):109
• All: 1 reference(s)