Nbl1^tm1Saki
Targeted Allele Detail

Summary

• Symbol: Nbl1^tm1Saki
• Name: NBL1, DAN family BMP antagonist; targeted mutation 1, S Sakiyama
• MGI ID: MGI:3042574
• Synonyms: Dan-
• Gene: Nbl1 Location: Chr4:138809595-138820304 bp, - strand Genetic Position: Chr4, 70.57 cM, cytoband D3
• Alliance: Nbl1^tm1Saki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89353
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 2.5 kb fragment including exons 2 and 3 was replaced with an MC1-Neo cassette. RT-PCR confirmed the absence of RNA expression in homozygotes. (J:89353)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nbl1 Mutation: 16 strains or lines available

References

• Original: J:89353 Ohtori S, et al., Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma. Mol Cell Neurosci. 2004 Mar;25(3):504-14
• All: 1 reference(s)