Bmp4^tm1.1Jfm
Targeted Allele Detail

Summary

• Symbol: Bmp4^tm1.1Jfm
• Name: bone morphogenetic protein 4; targeted mutation 1.1, James F Martin
• MGI ID: MGI:3042751
• Synonyms: Bmp4^null
• Gene: Bmp4 Location: Chr14:46620982-46628126 bp, - strand Genetic Position: Chr14, 23.95 cM
• Alliance: Bmp4^tm1.1Jfm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89237
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre-mediated excision of the loxP flanked exon 4 sequences of Bmp4^tm1Jfm left a single loxP site in place of exon 4. (J:89237)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp4 Mutation: 23 strains or lines available

References

• Original: J:89237 Liu W, et al., Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4489-94
• All: 5 reference(s)