Tg(Sry)4Ei
Transgene Detail

Summary

• Symbol: Tg(Sry)4Ei
• Name: transgene insertion 4, Eva M Eicher
• MGI ID: MGI:3042867
• Transgene: Tg(Sry)4Ei Location: unknown
• Alliance: Tg(Sry)4Ei page

Transgene origin

• Strain of Origin: C57BL/6J-Chr Y^POS

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Sry)4Ei expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sry (MGI:98660)

• Mutation details: This transgene consists of an inbred 129 strain derived 14.6 Kb genomic fragment containing the entire Sry open reading frame and no other genes. (J:31072)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

Notes

The single founder male carried two independent multiple transgene insertions designated Tg(Sry)4Ei (with a high copy number) and Tg(Sry)5Ei (with a low copy number). Only transgenics carrying Tg(Sry)4Ei alone were used in subsequent experiments.

References

• Original: J:31072 Eicher EM, et al., Sex reversal in C57BL/6J-YPOS mice corrected by a Sry transgene. Philos Trans R Soc Lond B Biol Sci. 1995 Nov 29;350(1333):263-8
• All: 5 reference(s)