Tg(NPPA-Bmp10)1Krc
Transgene Detail

Summary

• Symbol: Tg(NPPA-Bmp10)1Krc
• Name: transgene insertion 1, Kenneth R Chien
• MGI ID: MGI:3043003
• Transgene: Tg(NPPA-Bmp10)1Krc Location: unknown
• Alliance: Tg(NPPA-Bmp10)1Krc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(NPPA-Bmp10)1Krc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Bmp10 (MGI:1338820)

• Mutation details: A Bmp10 minigne (species unspecified) was expressed in the developing myocardium via the human NPPA promoter. The Bmp10 minigene was followed by 3' mouse Prm1 sequence, encompassing an intron and polyadenylation signal. (J:89404)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:89404 Pashmforoush M, et al., Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block. Cell. 2004 Apr 30;117(3):373-86
• All: 1 reference(s)