Elk1^tm2Nor
Targeted Allele Detail

Summary

• Symbol: Elk1^tm2Nor
• Name: ELK1, member of ETS oncogene family; targeted mutation 2, Alfred Nordheim
• MGI ID: MGI:3043408
• Synonyms: Elk-1^(RMCE16)
• Gene: Elk1 Location: ChrX:20799634-20816847 bp, - strand Genetic Position: ChrX, 16.45 cM, cytoband A1-A3
• Alliance: Elk1^tm2Nor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:89763
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, RMCE-ready)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with an FRT flanked PGK-neo cassette. The replacement was achieved by exchanging the FRT flanked hygromycin-thymidine kinase cassette in Elk^tm1Nor with the FRT flanked PGK-neo cassette via FLP-mediated recombination. (J:89763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elk1 Mutation: 8 strains or lines available

References

• Original: J:89763 Cesari F, et al., Elk-1 knock-out mice engineered by Flp recombinase-mediated cassette exchange. Genesis. 2004 Feb;38(2):87-92
• All: 1 reference(s)