Tg(MMTV-cre)AElee
Transgene Detail

Summary

• Symbol: Tg(MMTV-cre)AElee
• Name: transgene insertion A, Eva YHP Lee
• MGI ID: MGI:3043429
• Synonyms: MMTVCre^a
• Transgene: Tg(MMTV-cre)AElee Location: unknown
• Alliance: Tg(MMTV-cre)AElee page

Transgene origin

• Strain of Origin: CB6F1 x C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(MMTV-cre)AElee expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  virus	MMTV

• Mutation details: The expression of NLS-cre was restricted to mammary gland by MMTV-LTR sequence. The construct consisted of MMTV-LTR followed downstream by a genomic fragment of the rabbit beta globin gene in which nls-cre was inserted into exon 3. The rabbit beta globin and the polyadenylation signal was included. (J:90247)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	MMTV (virus) Summary of all recombinase alleles driven by MMTV.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:90247 Lin SC, et al., Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis. Cancer Res. 2004 May 15;64(10):3525-32
• All: 3 reference(s)