Runx1^tm3Spe
Targeted Allele Detail

Summary

• Symbol: Runx1^tm3Spe
• Name: runt related transcription factor 1; targeted mutation 3, Nancy A Speck
• MGI ID: MGI:3043614
• Synonyms: floxed Runx1 allele, Runx1^F, Runx1F
• Gene: Runx1 Location: Chr16:92398354-92622962 bp, - strand Genetic Position: Chr16, 53.7 cM
• Alliance: Runx1^tm3Spe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90431
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 4 of the locus. A neo and a third loxP site was downstream of the second loxP site in intron 4. Gene expression was not affected by the presence of the loxP sites. (J:107469)

Expression

In Mice Carrying this Mutation:	2 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx1 Mutation: 34 strains or lines available

References

• Original: J:90431 Li Z, et al., A new floxed allele of Runx1. MGI Direct Data Submission. 2004
• All: 52 reference(s)