FblGt(pGT1-3)1Jca
Gene trapped Allele Detail
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Symbol: |
FblGt(pGT1-3)1Jca |
Name: |
fibrillarin; gene trap 1, Javier F Caceres |
MGI ID: |
MGI:3043754 |
Synonyms: |
Fibrillarin- |
Gene: |
Fbl Location: Chr7:27869135-27878694 bp, + strand Genetic Position: Chr7, 16.67 cM, cytoband A1
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Alliance: |
FblGt(pGT1-3)1Jca page
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Mutant Cell Line: |
ES403 |
Germline Transmission: |
Earliest citation of germline transmission:
J:89938
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector Type: gene trap
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Mutation details: The endogenous locus was disrupted by insertion into intron 4 of the pGT1,-2, or-3 retroviral gene trap vector containing a splice acceptor site, beta-geo, and an SV40 poly-A signal. A fusion protein consisting of the N-terminal 132 amino acids of the Fbl protein fused to lacZ is expressed from the mutated locus.
(J:71817, J:89938)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Fbl Mutation: |
23 strains or lines available
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Original: |
J:89938 Newton K, et al., Fibrillarin is essential for early development and required for accumulation of an intron-encoded small nucleolar RNA in the mouse. Mol Cell Biol. 2003 Dec;23(23):8519-27 |
All: |
2 reference(s) |
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