Foxl2^tm1Gpil
Targeted Allele Detail

Summary

• Symbol: Foxl2^tm1Gpil
• Name: forkhead box L2; targeted mutation 1, Giuseppe Pilia
• MGI ID: MGI:3044226
• Synonyms: Foxl2^-
• Gene: Foxl2 Location: Chr9:98837495-98840601 bp, + strand Genetic Position: Chr9, 51.41 cM, cytoband E4
• Alliance: Foxl2^tm1Gpil page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90371
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region, contained within one exon, was replaced with a neo cassette. Southern blot confirmed recombination in mutant ES cells. (J:90371)

Disease models

Expression

In Mice Carrying this Mutation:	50 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxl2 Mutation: 15 strains or lines available

References

• Original: J:90371 Uda M, et al., Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development. Hum Mol Genet. 2004 Jun 1;13(11):1171-81
• All: 15 reference(s)