Brm2^C3H/HeJ
QTL Variant Detail

Summary

• QTL variant: Brm2^C3H/HeJ
• Name: brachyury modifier 2; C3H/HeJ
• MGI ID: MGI:3044387
• QTL: Brm2 Location: Chr15:82525376-82525499 bp Genetic Position: Chr15, cM position of peak correlated region/allele: 38.67 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C3H/HeJ

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:45873

Progeny with the most extreme tail length phenotype (T locus) that were derived again from the follwoing two crosses ((C3H females x B10-T males)F1 x B10 males and B10 females x (C3H females x B10-T males)F1 were analyzed for modifier loci effecting the expression of T. B10-T is a T mutation congenic. Quantitative trait analysis show a QTL locus, Brm2, significantly associated with a region of mouse Chromosome 15 including the D15Mit189 marker.

References

• Original: J:45873 Agulnik II, et al., Sex-specific modifiers of tail development in mice heterozygous for the brachyury (T) mutation. Mamm Genome. 1998 Feb;9(2):107-10
• All: 1 reference(s)