Summary |
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Variant origin |
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Variant description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:52119The strains BALB/cHeA and STS/A differ in the production of Il4 and Il10 after stimulation with concanavalin A (ConA). The genetic basis of this difference was analyzed using the recombinant congenic (RC) strains of the BALB/c - c - STS/Dem (CcS/Dem) series. The authors analyzed correlation between expression of Il4 and Il10 in 80 (CcS-20 x BALB/c)F2 hybrids after stimulation with ConA at a novel QTL, Cora1, marked by D5Mit63 on mouse Chromosome 5. Higher correlation was observed in homozygotes in either the BALB/c or STS/A allele than in heterozygotes (P = 0.0448). |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/22/2024 MGI 6.24 |
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