About   Help   FAQ
Igf1q2DU6i
QTL Variant Detail
Summary
QTL variant: Igf1q2DU6i
Name: insulin-like growth factor 1 QTL 2; DU6i
MGI ID: MGI:3044405
QTL: Igf1q2  Location: unknown  Genetic Position: Chr18, Syntenic
Variant
origin
Strain of Specimen:  DU6i
Variant
description
Allele Type:    QTL
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:66233

QTLs effecting body weight, obesity and muscle weight were found on mouse Chromosomes 1, 4, 5, 7, 11, 12, 13, and 17 and for leptin on 14 and insulin on chromosome 4. The cross used in the genome wide scan included approximately 400 F2 mice from a (DU6i x DBA/2)F1 intercross. DU6i is a strain selected for high body weight. 93 microsatellite markers were analyzed in the genome wide scan. Locations of the QTLs were provided by the authors and may not be equivalent to the closest microsatellites. Insulin-like growth factor 1 QTL 2 mapped to mouse Chromosome 18 to position 39.

References
Original:  J:66233 Brockmann GA, et al., Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice. Genome Res. 2000 Dec;10(12):1941-57
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory