Tg(Prnp-GFP/cre)1Blw
Transgene Detail

Summary

• Symbol: Tg(Prnp-GFP/cre)1Blw
• Name: transgene insertion 1, Carrolee Barlow
• MGI ID: MGI:3044724
• Synonyms: 98030B, 98030B Prion.GFPCre, Cre(+), Prion-Cre, Tg(Prnp-GFP/cre)98030Blw
• Transgene: Tg(Prnp-GFP/cre)1Blw Location: unknown
• Alliance: Tg(Prnp-GFP/cre)1Blw page

Transgene origin

• Strain of Origin: 129S6/SvEvTac

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prnp-GFP/cre)1Blw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Prnp

• Mutation details: Expression of an in-frame fusion of cre to GFP was driven by a modified prion promoter. The resulting transgene expresses Cre recombinase in all tissues during embryogenesis including the germline. (J:90777)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prnp (species not specified) Summary of all recombinase alleles driven by Prnp. Comparative matrix view of recombinase activities

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

This transgene is line 98030B of the laboratory in which the transgene originated. Homozygous transgenic mice are fertile and appear phenotypically normal.

References

• Original: J:90777 Scheel JR, et al., An inbred 129SvEv GFPCre transgenic mouse that deletes loxP-flanked genes in all tissues. Nucleic Acids Res. 2003 May 15;31(10):e57
• All: 9 reference(s)