Prlhr^tm1Askr
Targeted Allele Detail

Summary

• Symbol: Prlhr^tm1Askr
• Name: prolactin releasing hormone receptor; targeted mutation 1, Alain Stricker-Krongrad
• MGI ID: MGI:3044896
• Synonyms: GPR10^-
• Gene: Prlhr Location: Chr19:60455170-60456742 bp, - strand Genetic Position: Chr19, 56.52 cM
• Alliance: Prlhr^tm1Askr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90533
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: The sequence encoding exons 1-18 was replaced with a nuclear-localized LacZ gene and a neo. Southern blot and PCR confirmed recombination in tail DNA from mutants. (J:90533)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prlhr Mutation: 17 strains or lines available

References

• Original: J:90533 Gu W, et al., The prolactin-releasing peptide receptor (GPR10) regulates body weight homeostasis in mice. J Mol Neurosci. 2004;22(1-2):93-103
• All: 3 reference(s)