Dll1^tm1Mjo
Targeted Allele Detail

Summary

• Symbol: Dll1^tm1Mjo
• Name: delta like canonical Notch ligand 1; targeted mutation 1, Michael J Owen
• MGI ID: MGI:3044907
• Synonyms: Dll1^lox, Dll1^loxP
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^tm1Mjo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90630
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 3 and 4 were floxed following the transient cre-mediated excision of a floxed neo. (J:90630)

Expression

In Mice Carrying this Mutation:	25 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:90630 Hozumi K, et al., Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol. 2004 Jul;5(6):638-44
• All: 40 reference(s)