Tg(Dll1-Tbx18)20Akis
Transgene Detail

Summary

• Symbol: Tg(Dll1-Tbx18)20Akis
• Name: transgene insertion 20, Andreas Kispert
• MGI ID: MGI:3044917
• Synonyms: msd::Tbx18
• Transgene: Tg(Dll1-Tbx18)20Akis Location: unknown
• Alliance: Tg(Dll1-Tbx18)20Akis page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Dll1-Tbx18)20Akis expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tbx18 (MGI:1923615)

• Mutation details: The entire open reading frame of mouse Tbx18 was fused to a mesodermal specific promoter containing a 1495 bp mesodermal element from the 5' untranslated region of the Dll1 gene fused to the Dll1 minimal promoter. Two lines were generated, Tg(Dll1-Tbx18)2Akis and Tg(Dll1-Tbx18)20Akis, with the latter showing a more severe homozygous phenotype. The mesodermal specific promoter was first described in J:63760 (J:63760, J:90513)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:90513 Bussen M, et al., The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 2004 May 15;18(10):1209-21
• All: 4 reference(s)