Ntsr2^tm1Mfsc
Targeted Allele Detail

Summary

• Symbol: Ntsr2^tm1Mfsc
• Name: neurotensin receptor 2; targeted mutation 1, Marie-Francoise Suaud-Chagny
• MGI ID: MGI:3044928
• Synonyms: NT2R-KO
• Gene: Ntsr2 Location: Chr12:16703477-16710223 bp, + strand Genetic Position: Chr12, 7.98 cM
• Alliance: Ntsr2^tm1Mfsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90595
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 and all of exon 2 were replaced with a cassette containing TAG3/IRES/lacz/SV40pAMC1neo/PA. Southern blot of tail DNA confirmed recombination in mutants. (J:90595)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntsr2 Mutation: 22 strains or lines available

References

• Original: J:90595 Leonetti M, et al., Specific involvement of neurotensin type 1 receptor in the neurotensin-mediated in vivo dopamine efflux using knock-out mice. J Neurochem. 2004 Apr;89(1):1-6
• All: 1 reference(s)