Slc6a9^tm1Jtc
Targeted Allele Detail

Summary

• Symbol: Slc6a9^tm1Jtc
• Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9; targeted mutation 1, Joseph T Coyle
• MGI ID: MGI:3045030
• Synonyms: GlyT1-
• Gene: Slc6a9 Location: Chr4:117692240-117726502 bp, + strand Genetic Position: Chr4, 53.62 cM
• Alliance: Slc6a9^tm1Jtc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90689
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with aPGK-neo cassette via homologous recombination. RNA expression is absent in homozygous mice. (J:90689)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a9 Mutation: 24 strains or lines available

References

• Original: J:90689 Tsai G, et al., Gene knockout of glycine transporter 1: characterization of the behavioral phenotype. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8485-90
• All: 8 reference(s)