Or8a1^{tm11(Or8a1b)Mom}
Targeted Allele Detail

Summary

• Symbol: Or8a1^{tm11(Or8a1b)Mom}
• Name: olfactory receptor family 8 subfamily A member 1; targeted mutation 11, Peter Mombaerts
• MGI ID: MGI:3045150
• Synonyms: M72->M71, M72->M71-IRES-taulacZ, M72->M71-LacZ, Olfr151^tm11Mom, Or8a1^{tm11(Olfr160)Mom}
• Gene: Or8a1 Location: Chr9:37641273-37642357 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1^{tm11(Or8a1b)Mom} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90716
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Or8a1^{tm11(Or8a1b)Mom} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Or8a1b (MGI:1931271)

• Mutation details: The entire coding region of Olfr151 was replaced with Olfr160 and an IRES-lacZ gene introduced via homologous recombination. The GFP gene was fused after the stop codon and co-expressed with the mutant protein. (J:90716)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1 Mutation: 69 strains or lines available

References

• Original: J:90716 Feinstein P, et al., A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell. 2004 Jun 11;117(6):817-31
• All: 1 reference(s)