Or10a4^tm4Mom
Targeted Allele Detail

Summary

• Symbol: Or10a4^tm4Mom
• Name: olfactory receptor family 10 subfamily A member 4; targeted mutation 4, Peter Mombaerts
• MGI ID: MGI:3045157
• Synonyms: M71->P2-IRES-taulacZ, M71-P2, OR-lacZ
• Gene: Or10a4 Location: Chr7:106696674-106697621 bp, + strand Genetic Position: Chr7, 56.1 cM, cytoband F2
• Alliance: Or10a4^tm4Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90716
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: The entire coding region of Or10a4 was replaced with the coding sequence for Or8a1 and an IRES-taulacZ introduced via homologous recombination. The lacZ gene was fused after the stop codon and co-expressed with the mutant protein. (J:90716)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or10a4 Mutation: 22 strains or lines available

References

• Original: J:90716 Feinstein P, et al., A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell. 2004 Jun 11;117(6):817-31
• All: 4 reference(s)