Aqr^{Gt(PT1-ATG)193Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Aqr^{Gt(PT1-ATG)193Wrst}
• Name: aquarius; gene trap 193, Wolfgang Wurst
• MGI ID: MGI:3045413
• Synonyms: I.193
• Gene: Aqr Location: Chr2:113931642-114005788 bp, - strand Genetic Position: Chr2, 57.57 cM, cytoband E5-F2
• Alliance: Aqr^{Gt(PT1-ATG)193Wrst} page

Mutation origin

• Mutant Cell Line: I.193
• Germline Transmission: Earliest citation of germline transmission: J:31729
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: PT1-ATG Vector Type: gene trap
• Mutation details: The gene trap vector PT1-ATG inserted into the gene. A fusion transcript consisting of endogenous sequence fused to lacZ sequences is produced from this allele. However, wild-type transcripts are also expressed from this allele, suggesting that this is not a null mutation. (J:47963)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aqr Mutation: 66 strains or lines available

References

• Original: J:31729 Forrester LM, et al., An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1677-82
• All: 2 reference(s)