Rasgrf2^tm1Feig
Targeted Allele Detail

Summary

• Symbol: Rasgrf2^tm1Feig
• Name: RAS protein-specific guanine nucleotide-releasing factor 2; targeted mutation 1, Larry A Feig
• MGI ID: MGI:3045891
• Synonyms: ras-grf2(-), Rasgrf2^-
• Gene: Rasgrf2 Location: Chr13:92028519-92268164 bp, - strand Genetic Position: Chr13, 47.43 cM, cytoband C3-D1
• Alliance: Rasgrf2^tm1Feig page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:90111
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A neomycin gene was inserted into the first exon. PCR confirmed targeted recombination. (J:90111)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrf2 Mutation: 73 strains or lines available

References

• Original: J:90111 Tian X, et al., Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB. EMBO J. 2004 Apr 7;23(7):1567-75
• All: 5 reference(s)